Stages Leading Up To Osseointegration
STAGE I: Inflammatory response to bone damage during drilling procedures
STAGE II: Osteoclastic activity removes any clot or necrotic matter
Stages of Osseointegration
Primary Mesenchymal Cells differentiate into osteoblasts & lay down osteoid
Stages of Osseointegration
Woven bone laid down
Stages of Osseointegration
Lamellar Bone laid down
Surgical & Post Surgical Factors That Prevent Osseointegration
Heating of bone beyond 47 C
Poor vascular supply & low oxygen tension to site of implant placement
Micromovemnets beyond 150 um during initial healing phase at bone- implant interface